[1]陈彩凤 郑 焱 张丹群.C10orf99在扁平苔藓中的表达和意义[J].福建医药杂志,2020,42(05):121-122.
　CHEN Caifeng,ZHENG Yan,ZHANG Danqun.Expression and significance of C10orf99 in skin lichen planus[J].FUJIAN MEDICAL JOURNAL,2020,42(05):121-122.
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C10orf99在扁平苔藓中的表达和意义()
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《福建医药杂志》[ISSN:1002-2600/CN:35-1071/R]

卷:
42
期数:
2020年05期
页码:
121-122
栏目:
基础研究
出版日期:
2020-10-20

文章信息/Info

Title:
Expression and significance of C10orf99 in skin lichen planus
文章编号:
1002-2600(2020)05-0121-03
作者:
陈彩凤 郑 焱1 张丹群2
福建医科大学省立临床医学院 福建省立医院皮肤科(福州 350001)
Author(s):
CHEN Caifeng; ZHENG Yan; ZHANG Danqun
Department of Dermatology, Fujian Provincial Hospital,Clinical Medical College of Fujian Medical University, Fuzhou,Fujian 350001, China
关键词:
皮肤扁平苔藓;  C10orf99;  免疫组化
Keywords:
lichen planus;  C10orf99;  immunohistochemistry
分类号:
R758.65
文献标志码:
A
摘要:
目的 检测C10orf99在扁平苔藓皮损中的表达情况,探讨C10orf99在该病发病机制中的作用。方法 应用免疫组化SP法检测C10orf99在20例扁平苔藓皮损组织和10例正常皮肤组织中的表达情况。结果 C10orf99在扁平苔藓皮损中的表达水平明显高于其在正常皮肤组织中的表达水平,差异有统计学意义(P<0.001)。结论 C10orf99在扁平苔藓皮损中呈现高表达,可能在扁平苔藓的发生发展过程中起作用。
Abstract:
Objective To investigate the expression and significance of C10orf99 in lichen planus lesions.Methods Immunohistochemical method was carried out to detect the expression of C10orf99 in 20 patients with lichen planus and 10 specimens of normal skin.Results The expression of C10orf99 in the lesions of lichen planus was significantly higher than that in normal skin tissues, and the difference was statistically significant(P<0.001).Conclusion The expression of C10orf99 is increased in lichen planus and C10orf99 may play an important role in the occurrence and development of lichen planus.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金青年科学基金项目(81903220) 1 西安交通大学第二附属医院皮肤科(西安 710049); 2 通信作者,Email: danqunzhang@sina.com
更新日期/Last Update: 2020-10-20