[1]吴立忠 翁绳健 詹 洋 吴 星 郑 萍 康荣彬 李炜明.强骨宝方对生物型全髋术后髋臼假体周围骨密度的早期影响[J].福建医药杂志,2020,42(03):13-16.
　WU Lizhong,WENG Shengjian,ZHAN Yang,et al.Early effect of Qianggubao decoction on BMD around acetabular prosthsis after the cementless total hip arthroplasty[J].FUJIAN MEDICAL JOURNAL,2020,42(03):13-16.
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强骨宝方对生物型全髋术后髋臼假体周围骨密度的早期影响()
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《福建医药杂志》[ISSN:1002-2600/CN:35-1071/R]

卷:
42
期数:
2020年03期
页码:
13-16
栏目:
临床研究
出版日期:
2020-07-04

文章信息/Info

Title:
Early effect of Qianggubao decoction on BMD around acetabular prosthsis after the cementless total hip arthroplasty
文章编号:
1002-2600(2020)03-0013-04
作者:
吴立忠 翁绳健 詹 洋 吴 星 郑 萍 康荣彬 李炜明1
厦门大学附属福州第二医院关节外科(福州 350007)
Author(s):
WU Lizhong; WENG Shengjian; ZHAN Yang; WU Xing; ZHENG Ping; KANG Rongbin; LI Weiming.
The Fuzhou Second Hospital Affiliated to Xiamen University,Fuzhou,Fujian 350007,China
关键词:
强骨宝方;  骨密度;  全髋关节置换术
Keywords:
Qianggubao decoction;  bone mineral density;  total hip arthroplasty
分类号:
R681
文献标志码:
A
摘要:
目的 探讨强骨宝方对女性生物型全髋置换术后髋臼假体周围骨密度的早期影响。方法 随机将50例符合纳入标准的全髋置换患者分为强骨宝方组和对照组,术后1周均开始口服钙尔奇D 600 mg/d、罗盖全0.25 μg /d,其中,强骨宝方组患者每日另加1剂强骨宝方颗粒剂冲服,对照组不使用其他抗骨质疏松药物,连续服用药物3个月。两组均于术后1周、术后3、6、12个月测定髋臼假体周围分区骨密度,同时行髋关节功能评分。结果 47例患者获得完整随访。术后两组患者各分区骨密度均持续下降,Ⅲ区术后6个月及12个月强骨宝方组患者骨密度下降低于对照组,其差异有统计学意义(P<0.05),其余分区及时点骨密度比较的差异无统计学意义(P>0.05)。两组患者术后各时点髋关节功能评分比较的差异无统计学意义(P<0.05)。结论 中药强骨宝方应用于全髋关节置换术后可有效减少髋臼假体周围骨密度的下降。
Abstract:
Objective To investigate the early effect of Qianggubao decoction on bone mineral density(BMD)around acetabular prosthesis after the female cementless total hip arthroplasty.Methods Fifty patients who met the inclusion criteria were divided into the Qianggubao group and the control group randomly.All patients took therapy of Caltrate D 600mg/d and Rocaltrol 0.25 μg /d one week after total hip arthroplasty(THA)and lasted for three months.At the same time Qianggubao group took Qianggubao granules one dose per day for three months.The control group didnt take other anti-osteoporosis drug.BMD around acetabular prosthesis was detected at the point of 1 week after THA, 3 months after THA, 6 months after THA and 12 months after THA. The hip function was assessed by Harris scoring system at the same time.Results A total of 47 patients finished the study.BMD of all zones declined continuously.The loss of BMD in Zone Ⅲ of the Qianggubao group was less than control group at time of 6 and 12 months after THA.The difference between the two groups was statistically significant(P<0.05).There was no significant difference in other zones and other point between the two groups(P> 0.05).There were no statistically significant differrences in Harris scores between the two groups at any point.Conclusion Qianggubao decoction can decrease the loss of BMD around acetabular prosthesis after the cementless THA.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目:基金项目:福建省科技计划引导性项目(2017D0001); 福州市科技计划社会发展项目(2016-S-123-4)1 通信作者,Email:Liweiming0591@163.com
更新日期/Last Update: 2020-07-04