参考文献/References:
[1] Wang L F, Shi Z, Zhang S, et al. Review of bats and SARS[J]. Emerging infectious diseases, 2006, 12(12): 1834-1840.
[2] Chen Y,Guo D,Molecular mechanisms of coronavirus RNA capping and methylation[J].Virol Sin, 2016, 31(1): 3-11.
[3] Cui J,Li F,Shi Z L.Origin and evolution of pathogenic coronaviruses[J].Nat Rev Microbiol, 2019, 17(3): 181-192.
[4] Cauchemez S, Van Kerkhove M D, Riley S, et al. Transmission scenarios for Middle East Respiratory Syndrome Coronavirus(MERS-CoV)and how to tell them apart[J]. Euro surveill-ance: bulletin Europeen sur les maladies transmissibles=European communicable disease bulletin, 2013, 18(24).
[5] Zhong N S,Zheng B J,Li Y M, et al. Epidemiology and cause of severe acute respiratory syndrome(SARS)in Guangdong, Peoples Republic of China, in February, 2003[J].Lancet, 2003, 362(9393): 1353-1358.
[6] WHO. Summary of probable SARS cases with onset of illness from 1 November 2002 to 31 July 2003[EB/OL].[2020-01-12]. Geneva: World Health Organization, 2004.http://www.who.int/csr/sars/country/table2004_04_21/en/.
[7] WHO. Middle East respiratory syndrome coronavirus(MERS-CoV)[EB/OL]. Geneva:World Health Organization, 2020[2020-01-12]. http://www.who.int/emergencies/mers-cov/en/.
[8] Ziebuhr J,Snijder E J,Gorbalenya A E,Virus-encoded proteinases and proteolytic processing in the Nidovirales[J]. J Gen Virol, 2000, 81(4): 853-879.
[9] Hussain S,Pan J,ChenY,et al. Identification of novel subgenomic RNAs and noncanonical transcription initiation signals of severe acute respiratory syndrome coronavirus [J].J Virol, 2005, 79(9): 5288-5295.
[10] Zhu N, Zhang D, Wang W, et al.A Novel Coronavirus from Patients with Pneumonia in China, 2019[J]. New England Journal of Medicine, 2020.
[11] Fehr A R, Perlman S. Coronaviruses: an overview of their replication and pathogenesis[M]. New York: Humana Press, 2015: 1-23.
[12] Su S,Wong G,Shi W F,et al. Epidemiology, Genetic Recombination, and Pathogenesis of Coronaviruses[J].Trends Microbiol,2016, 24(6): 490-502.
[13] Zhou P,Fan H,Lan T, et al. Fatal swine acute diarrhoea syndrome caused by an HKU2-related coronavirus of bat origin.[J].Nature, 2018, 556(7700): 255-258.
[14] Ji W,Wang W,Zhao X F,et al. Homologous recombination within the spike glycoprotein of the newly identified coronavirus may boost cross-species transmission from snake to human.[J] J Med Virol,2020.
[15] Shi Z L, Zhou P, Yang X L, et al. Discovery of a novel coronavirus associated with the recent pneumonia outbreak in humans and its potential bat origin[J]. bioRxiv, 2020.
[16] Chan J F W, Yuan S, Kok K H, et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster[J]. The Lancet, 2020.
[17] Sabir J S M, Lam T T Y, Ahmed M MM, et al. Co-circulation of three camel coronavirus species and recombination of MERS-CoVs in Saudi Arabia[J]. Science, 2016, 351(6268): 81-84.
[18] Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China[J]. The Lancet, 2020.
[19] Zhu N, Zhang D, Wang W, et al. A Novel Coronavirus from Patients with Pneumonia in China, 2019[J]. New England Journal of Medicine, 2020.
[20] Li Q,Guan X H,Wu P,et al. Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia[J].N Engl J Med, 2020.
[21] Chen N,Zhou M,Dong X et al.Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study[J]. The Lancet, 2020.
[22] Wang C, Horby P W, Hayden F G, et al. A novel coronavirus outbreak of global health concern[J]. The Lancet, 2020.
[23] WHO.Clinical management of severe acute respiratory infection when Novel coronavirus(nCoV)infection is suspected: Interim Guidance:World Health Organization,2020[R/OL].[2020-01-12].https://www.who.int/docs/default-source/coronaviruse/clinical-management-of-novel-cov.pdf?sfvrsn=bc7da517-2.
[24] Heymann D L. Data sharing and outbreaks: best practice exemplified[J]. The Lancet, 2020.
[25] 李凯述,陈建荣,蔡映云.人工智能专家系统在呼吸系统疾病中的应用[J].国外医学内科学分册,2005,32(12):513-515,520.
[26] Su K,Xu L,Li G Q,et al. Forecasting influenza activity using self-adaptive AI model and multi-source data in Chongqing, China[J].EBioMedicine, 2019, 47: 284-292.
[27] Meinert E,Alturkistani A,Foley K A,et al. Blockchain Implementation in Health Care: Protocol for a Systematic Review[J].JMIR Res Protoc, 2019, 8(2): e10994.
[28] Sharma A, Kumar R. An optimal routing scheme for critical healthcare HTH services-an IOT perspective[C]//2017 Fourth International Conference on Image Information Processing(ICIIP). IEEE, 2017: 1-5.
[29] Engelhardt M A. Hitching healthcare to the chain: An introduction to blockchain technology in the healthcare sector[J]. Technology Innovation Management Review, 2017, 7(10).
[30] Saravanan M, Shubha R, Marks A M, et al. SMEAD: A secured mobile enabled assisting device for diabetics monitoring[C].2017 IEEE International Conference on Advanced Networks and Telecommunications Systems(ANTS). IEEE, 2017: 1-6.
[31] Chattu V K, Nanda A, Chattu S K, et al. The emerging role of blockchain technology applications in routine disease surveillance systems to strengthen global health security[J]. Big Data and Cognitive Computing, 2019, 3(2): 25.
[32] Katuwal G J, Pandey S, Hennessey M, et al. Applications of blockchain in healthcare: current landscape & challenges[J]. arXiv preprint arXiv:1812.02776, 2018.
[33] World Health Organization. Infection prevention and control during health care when novel coronavirus(nCoV)infection is suspected: interim guidance, January 2020[R]. World Health Organization, 2020.
[34] Wong C K, Lam C W K, Wu A K L, et al. Plasma inflamma-tory cytokines and chemokines in severe acute respiratory syndrome[J]. Clinical & Experimental Immunology, 2004, 136(1): 95-103.
[35] Mahallawi W H, Khabour O F, Zhang Q, et al. MERS-CoV infection in humans is associated with a pro-inflammatory Th1 and Th17 cytokine profile[J]. Cytokine, 2018, 104: 8-13.
[36] Munster V J, Koopmans M, van Doremalen N, et al. A Novel Coronavirus Emerging in China-Key Questions for Impact Assessment[J]. New England Journal of Medicine, 2020.