参考文献/References:
[1] Smith E E, Schneider J A, Wardlaw J M,et al. Cerebral microinfarcts: the invisible lesions[J].Lancet Neurol,2012,11(3):272-282.
[2] Pantoni L. Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges[J].Lancet Neurol,2010,9(7):689-701.
[3] Kaul S, Alladi S, Jabeen S A, et al.Intracranial atherosclerosis is the most common stroke subtype: ten-year data from hyderabad stroke registry(India)[J].Ann Indian Acad Neurol, 2018,21(3):209-213.
[4] Chen X,Wang J,Shan Y,et al. Cerebral small vessel disease: neuroimaging markers and clinical implication[J].J Neurol,2018.[Epub ahead of print]
[5] Tchistiakova E,Anderson N D,Greenwood C E.Combined effects of type 2 diabetes and hypertension associated with cortical thinning and impaired cerebrovascular reactivity relative to hypertension alone in older adults[J]. Neuroimage Clin,2014,5:36-41.
[6] Jefferson A L, Cambronero F E, Liu D,et al.Higher aortic stiffness is related to lower cerebral blood flow and preserved cerebrovascular reactivity in older adults[J].Circulation, 2018,138(18):1951-1962.
[7] Blair G W, Doubal F N, Thrippleton M J, et al.Magnetic resonance imaging for assessment of cerebrovascular reactivity in cerebral small vessel disease: A systematic review[J].J Cereb Blood Flow Metab,2016,36(5):833-841.
[8] Kozera G M, Dubaniewicz M, Zdrojewski T, et al. SOPKARD Study Group.Cerebral vasomotor reactivity and extent of white matter lesions in middle-aged men with arterial hypertension: a pilot study[J]. Am J Hypertens,2010,23(11):1198-1203.
[9] Staszewski J, Skrobowska E, Piusińska-Macoch R, et al. Cerebral and extracerebral vasoreactivity in patients with different clinical manifestations of cerebral small-vessel disease: data from the significance of hemodynamic and hemostatic factors in the course of different manifestations of cerebral small-vessel disease study[J].J Ultrasound Med,2018. [Epub ahead of print]
[10] Intharakham K, Suwanprasert K, Muengtaweepongsa S.Correlation between decreased parasympathetic activity and reduced cerebrovascular reactivity in patients with lacunar infarct[J].Curr Neurovasc Res, 2017,14(1):65-70.
[11] Agyérbetegségek O K,Pánczél G. Impairment of vasoreactivity in brainstem and hemispheral small vessel disease: comparative study[J]. Nagy Z Ideggyogy Sz,2002,55(3-4):95-101.
[12] Menendez-Gonzalez M, Garcia-Garcia J, Calleja S,et al.Vasomotor reactivity is similarly impaired in patients with Alzheimers disease and patients with amyloid hemorrhage[J]. J Neuroimaging,2011,21(2):e83-85
[13] Pfefferkorn T. Reduced cerebrovascular CO2 reactivity in CADASIL: A transcranial Doppler sonography study[J].Stroke,2001,32(1):17-21.
[14] Liem M K, Lesnik Oberstein S A, Haan J,et al.Cerebrovascular reactivity is a main determinant of white matter hyperintensity progression in CADASIL[J].AJNR Am J Neuroradiol,2009,30(6):1244-1247
[15] Moreton F C, Cullen B,Delles C,et al.Vasoreactivity in CADASIL: Comparison to structural MRI and neuropsychology[J].J Cereb Blood Flow Metab, 2018,38(6):1085-1095.
[16] Campolo J, De Maria R, Frontali M,et al. Impaired vasoreactivity in mildly disabled CADASIL patients[J].J Neurol Neurosurg Psychiatry, 2012,83(3):268-274.
[17] Dziewulska D, Lewandowska E. Pericytes as a new target for pathological processes in CADASIL[J].Neuropathology, 2012,32(5):515-521.
[18] Rodan L H,Poublanc J, Fisher J A,et al.Cerebral hyperperfusion and decreased cerebrovascular reactivity correlate with neurologic disease severity in MELAS[J].Mitochondrion, 2015,22:66-74.
[19] Segura T, Ayo-Martín O, Gómez-Fernandez I,et al.Cerebral hemodynamics and endothelial function in patients with Fabry disease[J].BMC Neurol,2013,13:170.
[20] Khorvash F, Masaeli A, Shaygannejad V,et al.Vasomotor reactivity comparison in multiple sclerosis patients with white matter lesions and nonmultiple sclerosis subjects with white matter lesions in brain magnetic resonance imaging[J].Adv Biomed Res,2016,5:23.
[21] Jovanovi Z B, Pavlovi A M, Pekmezovi T,et al.Transcranial Doppler assessment of cerebral vasomotor reactivity in evaluating the effects of vinpocetine in cerebral small vessel disease: a pilot study[J].Ideggyogy Sz,2013,66(7-8):263-268.
[22] Inoue N, Harada M. Effect of perindopril on vasoreactivity in patients with hypertensive chronic cerebrovascular disease. A comparative analysis of different brain structures[J].Arzneimittelforschung,2008,58(7):317-322.
[23] Forteza A, Romano J G, Campo-Bustillo I,et al. High-dose atorvastatin enhances impaired cerebral vasomotor reactivity[J].J Stroke Cerebrovasc Dis,2012,21(6):487-492.