[1]谢永进,邓琳,罗金英.双胎妊娠胎盘早剥母儿妊娠结局及相关因素分析[J].福建医药杂志,2022,44(05):1-4.
　XIE Yongjin,DENG Lin,LUO Jinying.Pregnancy outcomes and related factors in twin pregnancy with placental abruption[J].FUJIAN MEDICAL JOURNAL,2022,44(05):1-4.
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双胎妊娠胎盘早剥母儿妊娠结局及相关因素分析()
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《福建医药杂志》[ISSN:1002-2600/CN:35-1071/R]

卷:
44
期数:
2022年05期
页码:
1-4
栏目:
临床研究
出版日期:
2022-10-15

文章信息/Info

Title:
Pregnancy outcomes and related factors in twin pregnancy with placental abruption
文章编号:
1002-2600（2022）05-0001-04
作者:
谢永进; 邓琳1; 罗金英2
福建省妇幼保健院 福建医科大学妇儿临床医学院（福州 350001）
Author(s):
XIE Yongjin; DENG Lin; LUO Jinying
College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fujian Maternity and Child Health Hospital, Fuzhou, Fujian 350001, China
关键词:
双胎妊娠; 胎盘早剥; 妊娠结局; 相关因素
Keywords:
twin pregnancy;  placental abruption;  pregnancy outcomes;  related factors
分类号:
R714.7
文献标志码:
B
摘要:
目的 回顾性分析双胎妊娠相关资料，探讨双胎妊娠胎盘早剥的母儿妊娠结局及相关影响因素，提高对双胎妊娠胎盘早剥的认识和处理能力。方法 以2015年6月至2018年5月福建省妇幼保健院双胎妊娠孕妇为研究对象，选取胎盘早剥（病例组）30例，同期非胎盘早剥（对照组）60例，分析两组妊娠结局的差异和可能的相关因素。 结果 研究期间双胎胎盘早剥的发生率为2.26%（30/1 325）。病例组发生胎儿窘迫的概率显著高于对照组（P<0.05）；高龄孕妇、单绒毛膜双胎、产前贫血是双胎发生胎盘早剥的危险因素（P<0.05）；单绒毛膜双胎和产前贫血是独立危险因素[OR=4.809，95%CI:（1.366，16.935）；OR=2.930，95%CI:（1.048,8.193）]。结论 胎盘早剥增加了双胎胎儿窘迫的发生，双胎妊娠胎盘早剥与高龄孕妇、单绒毛膜、产前贫血等因素相关。
Abstract:
Objective To retrospectively analyze the maternal and neonatal outcomes and possible associated factors of placental abruption in twin pregnancies so as to improve the awareness and ability to deal with placental abruption in twin pregnancies .Methods Ninety cases of twin pregnant women delivered in Fujian Maternity and Child Health Hospital, Gynecology and Pediatrics Clinical Medical College of Fujian Medical University from June 2015 to May 2018 were involved, among which, 30 cases of placental abruption were chosen as case group and 60 cases of non-placental abruption as control group.The differences in pregnancy outcomes between the two groups and the possible related factors were analyzed. Results The incidence rate of twin placental abruption was 2.26% (30/1 325) during the study period. The incidence of fetal distress in case group was significantly higher than that in control group (P<0.05). Single factor analysis showed that advanced maternal age, monochorionic twin and prenatal anemia were the risk factors of placental abruption(P<0.05).Multiple logistic regression analysis showed that monochorionic twin and prenatal anemia were independent risk factors [OR=4.809, 95%CI: (1.366,16.935) and OR=2.930, 95%CI: (1.048，8.193)]. Conclusion Placental abruption increased the incidence of twin fetal distress when compared with non-twin pregnancies.Placental abruption was associated with advanced maternal age, monochorionic membranes and prenatal anemia.

参考文献/References:

[1] Okby R, Al Atawana A, Wainstock T, et al.Placental abruption in twin pregnancies, risk factors and perinatal outcomes[J]. Am J Obstet Gynecol, 2017, 216: S551.
[2] Mukherjee S, Bawa A K, Sharma S, et al.Retrospective study of risk factors and maternal and fetal outcome in patients with abruptio placentae[J].J Nat Sci Biol Med, 2014, 5(2): 425-428.
[3] Martin J A, Hamilton B E, Osterman M J K, et al.Births: Final Data for 2016[J].Natl Vital Stat Rep, 2018, 67(1): 1-55.
[4] 中华医学会妇产科学分会产科学组.胎盘早剥的临床诊断与处理规范（第1版）[J].中华妇产科杂志, 2012, 47(12): 957-958.
[5] 谢幸, 孔北华, 段涛.妇产科学[M].9版.北京：人民卫生出版社, 2018：150-152.
[6] 王卫平, 孙锟, 常立文.儿科学[M].9版.北京：人民卫生出版社, 2018：93-120.
[7] de Moreuil C, Hannigsberg J, Chauvet J, et al.Factors associated with poor fetal outcome in placental abruption[J].Pregnancy Hypertens, 2021, 23: 59-65.
[8] 孙芳, 陈凤华, 李穗芬.胎儿窘迫相关临床因素702例分析[J].中国实用妇科与产科杂志, 2005, 21(9): 565-566.
[9] Pérez M L M, Hernández Garre J M, Pérez P E.Analysis of factors associated with variability and acidosis of the umbilical artery pH at birth[J].Front Pediatr, 2021, 9: 650555.
[10] Stearns K, Tsaih S W, Palatnik A.Racial and ethnic disparities in maternal and neonatal outcomes among women with chronic hypertension[J].Am J Perinatol, 2022,39(10):1033-1041.
[11] Martinelli K G, Garcia é M, Santos Neto E T D, et al.Advanced maternal age and its association with placenta praevia and placental abruption: a meta-analysis[J].Cad Saude Publica, 2018, 34(2): e00206116.
[12] Masini G, Tordini C, Pietrosante A, et al.Prediction of pregnancy complications by second-trimester uterine artery Doppler assessment in monochorionic twins[J].Clin Ultrasound.2019,47(7): 399-404.
[13] 庄艳艳.20年间双胎妊娠并发症变化及妊娠结局的比较分析[J].现代妇产科进展, 2014，23(1):40-43.
[14] Hasegawa J, Nakamura M, Hamada S, et al.Capable of identifying risk factors for placental abruption[J].J Matern Fetal Neonatal Med, 2014, 27(1): 52-56.
[15] Shi H, Chen L, Wang Y, et al.Severity of anemia during pregnancy and adverse maternal and fetal outcomes[J].JAMA Netw Open, 2022, 5(2): e2147046.
[16] 中华医学会围产医学分会.妊娠期铁缺乏和缺铁性贫血诊治指南[J].中华围产医学杂志, 2014, 17(7): 451-454.

相似文献/References:

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备注/Memo

备注/Memo:
基金项目：福建省自然科研基金项目（2018J01234）
1福建医科大学妇儿临床医学院；2通信作者，E-mail：luo9903378@126.com
更新日期/Last Update: 2022-10-15