[1]冯爱然,洪苓苓,叶玲,等.快速现场评价技术在肺癌诊断中的应用价值[J].福建医药杂志,2022,44(03):5-8.
　FENG Airan,HONG Lingling,YE Ling,et al.Application value of rapid on-site evaluation technology in diagnosis of lung cancer[J].FUJIAN MEDICAL JOURNAL,2022,44(03):5-8.
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快速现场评价技术在肺癌诊断中的应用价值()
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《福建医药杂志》[ISSN:1002-2600/CN:35-1071/R]

卷:
44
期数:
2022年03期
页码:
5-8
栏目:
临床研究
出版日期:
2022-06-15

文章信息/Info

Title:
Application value of rapid on-site evaluation technology in diagnosis of lung cancer
文章编号:
1002-2600(2022)03-0005-04
作者:
冯爱然; 洪苓苓; 叶玲; 杨栋勇1
福建省厦门市第五医院呼吸与危重症医学科(厦门 361101)
Author(s):
FENG Airan; HONG Lingling; YE Ling; YANG Dongyong. Department of Respiration and Critical Care
Medicine,the Fifth Hospital of Xiamen,Xiamen, Fujian 361101,China
关键词:
快速现场评价;  活体组织检查;  病理;  肺癌
Keywords:
rapid on-site evaluation;  biopsy;  pathology;  lung cancer
分类号:
R734.2
文献标志码:
B
摘要:
目的 探讨快速现场评价(rapid on-site evaluation,ROSE)技术在肺癌诊断中的临床价值。方法 收集疑似肺癌病例45例,活检标本后同时行ROSE技术及病理检查,以病理学检查为金标准,计算ROSE检查的符合率。记录两者出具报告所需的时间。结果 45例患者中,经支气管镜检查的病例有29例,CT引导下经皮肺穿刺检查12例,胸膜活检术及胸腔闭式引流术4例。病理标本中均可诊断肺癌,ROSE标本44例可诊断肺癌,1例患者不能明确诊断,ROSE技术的符合率达97.78%。ROSE报告取得标本后的4～52 min内出具,平均时间(13.58±8.67)min; 病理报告在2 832～15 885 min获得,平均时间(6 908.76±5 260.39)min,两种诊断比较,差异有统计学意义(t=8.79,P=0.001)。结论 ROSE技术与病理学检查诊断符合率高,ROSE技术较病理学检查具有诊断快速的优势。
Abstract:
Objective To explore the clinical significance of rapid on-site evaluation(ROSE)in the diagnosis of lung cancer.Methods A total of 45 cases of suspected lung cancer were collected, and ROSE technique and pathological examination were performed simultaneously after biopsy.The coincidence rate of ROSE examination was calculated by taking pathological examination as the gold standard.The time required for both to produce a report was recorded. Results Of the 45 biopsy specimens, there were 29 cases obtained with bronchoscopy, 12 cases obtained with CT-guided percutaneous lung puncture, and 4 cases obtained with pleural biopsy and closed thoracic drainage.All of lung cancer could be diagnosed in pathological specimens, 44 cases could be diagnosed in ROSE specimens,1 case could not be clearly diagnosed.The coincidence rate of ROSE technique was 97.78%.The ROSE report was issued within 4～52 min after obtaining the specimen, with an average time of(13.58±8.67)min; the pathological report was obtained within 2 832～15 885 min, with an average time of(6 908.76±5 260.39)min.The difference between the two diagnoses was statistically significant(t=8.79,P=0.001).Conclusion ROSE technology has a high coincidence rate with pathological examination, and ROSE technology has the advantage of rapid diagnosis compared with pathological examination.

参考文献/References:

[1] 郑荣寿,孙可欣,张思维,等.2015年中国恶性肿瘤流行情况分析[J].中华肿瘤杂志,2019,41(1):19-28.
[2] Zeng H M,Chen W Q,Zheng R S,et al.Changing cancer survival in China during 2003-15:a pooled analysis of 17 population-based cancer registries[J].Lancet Global Health,2018,6(5):e555-e567.
[3] Ferlay J,Colombet M,Soerjomataram I,et al.Cancer incidence and mortality patterns in Europe:Estimates for 40 countries and 25 major cancers in 2018[J].European Journal of Cancer, 2018, 103: 356-387.
[4] 王霞,杨宇飞.肿瘤康复的研究进展[J].世界科学技术-中医药现代化,2015,17(12):86-92.
[5] Wohlschlager J,Darwiche K,Ting S,et al.Rapid on-site evaluation(ROSE)in cytological diagnostics of pulmonary and mediastinal diseases[J].Pathologe,2012,33(4):308-315.
[6] 张红.快速现场评价的作用与局限性[J].中华结核和呼吸杂志,2018,41(6):509-510.
[7] Wang J,Zhao Y P,Chen Q Q,et al.Diagnostic value of rapid on-site evaluation during transbronchial biopsy for peripheral lung cancer[J].Jpn J Clin Oncol,2019,49(6):501-505.
[8] Collins B T,Chen A C,Wang J F,et al.Improved laboratory resource utilization and patient care with the use of rapid on-site evaluation for endobronchial ultrasound fine-needle aspiration biopsy[J].Cancer Cytopathol,2013,121(10):544-551.
[9] Guo H,Liu S,Guo J,et al.Rapid on-site evaluation during endo-bronchial ultrasound-guided transbronchial needle aspiration for the diagnosis of hilar and mediastinal lymphadenopathy in patients with lung cancer[J].Cancer Lett,2016,371(2):182-186.
[10] Hopkins E,Moffat D,Smith C,et al.Accuracy of rapid on-site evaluation of endobronchial ultrasound guided transbronchial needle aspirates by respiratory registrars in training and medical scientists compared to specialist pathologists-an initial pilot study[J].J Thorac Dis,2018,10(7):3922-3927.
[11] Oki M,Saka H,Kitagawa C,et al.Rapid on-site cytologic evaluation during endobronchial ultrasound-guided transbronchial needle aspiration for diagnosing lung cancer:a randomized study[J].Respiration,2013,85(6):486-492.
[12] Madan N K,Madan K,Jain D,et al.Utility of conventional transbronchial needle aspiration with rapid on-site evaluation(c-TBNA-ROSE)at a tertiary care center with endobronchial ultrasound(EBUS)facility[J].Cytol, 2016,33(1):22-26.
[13] Saha K,Sengupta M.Computed tomography guided fine needle aspiration cytology of pulmonary mass lesions in a tertiary care hospital:A two-year prospective study[J].medknow publications & media pvt ltd,2014,7(2):177.
[14] Nandwani R,Krishnan M G,Chandrakar S K,et al.Role and accuracy of rapid on-site evaluation of ct:guided fine needle aspiration cytology of throracic lesions[J].Journal of Evolution of Medical & Dental Sciences,2014,3(23):6526-6538.

备注/Memo

备注/Memo:
基金项目:福建省科技计划引导性项目(2020D024)
1 通信作者,福建医科大学附属第二医院呼吸与危重症医学科
更新日期/Last Update: 2022-06-15