[1]郭晓峰,朱鹏举,王程毅,等.儿童重症肺炎支原体肺炎185例影响因素分析[J].福建医药杂志,2021,43(06):1-5.
　GUO Xiaofeng,ZHU Pengju,WANG Chengyi,et al.Analysis of influencing factors of 185 children with severe mycoplasma pneumoniae pneumonia[J].FUJIAN MEDICAL JOURNAL,2021,43(06):1-5.
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儿童重症肺炎支原体肺炎185例影响因素分析()
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《福建医药杂志》[ISSN:1002-2600/CN:35-1071/R]

卷:
43
期数:
2021年06期
页码:
1-5
栏目:
临床研究
出版日期:
2021-12-15

文章信息/Info

Title:
Analysis of influencing factors of 185 children with severe mycoplasma pneumoniae pneumonia
文章编号:
1002-2600(2021)06-0001-05
作者:
郭晓峰; 朱鹏举1; 王程毅2; 赵涵3; 刘光华; 王世彪
上海交通大学医学院附属上海儿童医学中心福建医院 福建省妇幼保健院 福建医科大学附属医院 福建省儿童医院(福州 350011)
Author(s):
GUO Xiaofeng;  ZHU Pengju;  WANG Chengyi;  ZHAO Han;  LIU Guanghua;  WANG Shibiao
Department of Pediatrics, Fujian Children's Hospital,Fujian Maternity and Child Health Hospital,Affiliated Hospital of Fujian Medical University, Fujian Branch of Shanghai Children's Medical Center Affiliated to Shanghai Jiaotong University School of Medicine,Fuzhou,Fujian 350011, China
关键词:
肺炎支原体; 重症;  三代死亡风险评分;  儿童
Keywords:
mycoplasma pneumonia; severity;  PRISM Ⅲ;  children
分类号:
R563.1
文献标志码:
B
摘要:
目的 探讨重症肺炎支原体肺炎(MPP)的影响因素。方法 回顾性分析我院2016年1月至2018年12月收治的185例重症MPP患儿的临床资料,并根据PRISM Ⅲ评分将患儿分为低危组(PRISM评分≤3分)91例、中危组(PRISM评分3～8分)71例和高危组(PRISM评分大于>8分)23例。结果 3组间临床特征比较,2/3及更多的肺叶受累所占比例、2个或更多系统的肺外并发症所占比例、气管插管所占比例差异有统计学意义(P<0.05)。3组间实验室检查比较,血红蛋白和前白蛋白(PA)水平降低,而红细胞体积分布宽度(RDW)和D-二聚体(D-D)水平升高,差异均具有统计学意义(P<0.05)。在有序logistic回归模型中,我们发现2个或更多系统肺外并发症所占比例[OR=0.369,95%CI(0.161,0.848),P=0.019]、气管插管所占比例[OR=0.451,95%CI(0.215,0.945),P=0.035]、RDW水平[OR=1.358,95%CI(1.154,1.598),P<0.001)]与PRISM Ⅲ评分呈正相关,而PA水平[OR=0.883,95%CI(0.839,0.930),P<0.001]与PRISM Ⅲ评分呈负相关。结论 我们认为2个或更多系统的肺外并发症所占比例、气管插管所占比例、RDW水平和PA水平是患儿重症MPP的影响因素。
Abstract:
Objective This study is aimed to analyze influencing factors which could warn the progression of severe mycoplasma pneumoniae pneumonia(MPP).Methods We retrospectively reviewed the data of 185 children with severe MPP who were treated in our hospital between January 2016 and December 2018.We stratified the children according to PRISM Ⅲ scores, 91 cases were in the low group(≤3 scores), 71 cases were in the medium group(3-8 scores), and 23 cases were in the high group(>8 scores).Results There were statistical significances(P<0.05)in the proportions of those with 2/3 or more pulmonary lobes affected, extrapulmonary complications of two or more systems, and intubation among the three groups.Hemoglobin and pre-albumin levels decreased, while red blood cell volume distribution width(RDW)and D-dimer levels increased among the three groups, with statistical significance(P<0.05).In the ordered logistic regression model, there were positive correlations between extrapulmonary complications of two or more systems[OR=0.369,95%CI(0.161,0.848),P=0.019],intubation[OR=0.451,95%CI(0.215,0.945),P=0.035], RDW level[OR=1.358,95%CI(1.154,1.598),P<0.001)] and PRISM Ⅲ scores.In contrast, there was a negative correlation between pre-albumin level[OR=0.883,95%CI(0.839,0.930),P<0.001] and PRISM Ⅲ scores.Conclusion We consider extrapulmonary complications of two or more systems, intubation, RDW level, and pre-albumin level may be influencing factors of severe MPP.

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备注/Memo

备注/Memo:
1 福建省宁德市霞浦县医院儿科; 2 通信作者,Email:wangchengyi79@126.com; 3 福建医科大学2018级学生
更新日期/Last Update: 2021-12-15