[1]刘勇乐 朱 慧 刘素佳.极早产儿支气管肺发育不良影响因素分析[J].福建医药杂志,2020,42(05):36-38.
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极早产儿支气管肺发育不良影响因素分析()
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《福建医药杂志》[ISSN:1002-2600/CN:35-1071/R]

卷:
42
期数:
2020年05期
页码:
36-38
栏目:
临床研究
出版日期:
2020-10-20

文章信息/Info

文章编号:
1002-2600(2020)05-0036-03
作者:
刘勇乐 朱 慧 刘素佳1
福建医科大学省立临床医学院 福建省立医院新生儿重症医学科(福州 350001)
关键词:
极早产儿;  支气管肺发育不良;  影响因素
分类号:
R722
文献标志码:
B
摘要:
目的 分析<32周极早产儿支气管肺发育不良(bronchopulmonary dysplasia,BPD)的影响因素,为临床预防BPD提供依据。方法 回顾性收集我院新生儿重症监护病房收治的胎龄<32周的124例早产儿临床资料,按BPD的诊断标准,分为BPD组(50例)和非BPD组(74例),比较两组新生儿期和母孕期特点,多因素logistic回归分析BPD的影响因素。结果 BPD发生率为40.32%。单因素分析结果显示,胎龄、出生体质量、5 min Apgar评分、动脉导管未闭、晚发型败血症、有创机械通气、无创辅助通气及吸氧时间、开始肠内营养时间、达全肠道喂养时间、生后14 d内每日平均体质量增长均与BPD的发生有关,差异均有统计学意义(P<0.05)。多因素logistic回归分析结果显示,无创辅助通气时间(OR=1.460,95%CI 1.089～1.958)、吸氧时间(OR=1.412,95%CI 1.153～1.731)是极早产儿发生BPD的独立危险因素。结论 BPD发生与多因素有关,严格把握无创辅助通气的使用及停用指征,缩短用氧时间可减少BPD的发病风险。

参考文献/References:

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备注/Memo

备注/Memo:
1 福建省妇幼保健院 福建医科大学附属医院新生儿科
更新日期/Last Update: 2020-10-20