[1]张忠龙 吴汝香.学龄前后患儿食物不耐受特异性IgG抗体检测分析[J].福建医药杂志,2019,41(06):19-135.
　ZHANG Zhonglong,WU Ruxiang..Analysis of food intolerance-specific IgG antibodies in children before and after school age[J].FUJIAN MEDICAL JOURNAL,2019,41(06):19-135.
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学龄前后患儿食物不耐受特异性IgG抗体检测分析()
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《福建医药杂志》[ISSN:1002-2600/CN:35-1071/R]

卷:
41
期数:
2019年06期
页码:
19-135
栏目:
临床研究
出版日期:
2019-12-25

文章信息/Info

Title:
Analysis of food intolerance-specific IgG antibodies in children before and after school age
文章编号:
1002-2600(2019)06-0019-04
作者:
张忠龙 吴汝香
福建省福州儿童医院(福州 350005)
Author(s):
ZHANG Zhonglong; WU Ruxiang.
Fuzhou Childrens Hospital of Fujian Province, Fuzhou, Fujian 350005, China
关键词:
学龄前后;  患儿;  食物不耐受;  IgG抗体
Keywords:
before and after school age;  children;  food intolerance;  IgG antibodies
分类号:
R593.1
文献标志码:
B
摘要:
目的 探讨学龄前后患儿食物不耐受表现形式及阳性率分布特征,为降低食物不耐受的发展提供科学喂养依据。方法 采用ELISA法对学龄前后1 626例消化道、皮肤疾病患儿进行常见的14种食物不耐受的特异性IgG抗体检测,判断级别,分析食物不耐受程度。结果 所有患儿IgG抗体阳性率为88.0%。两种疾病患儿:不耐受阳性率相近(88.2%、86.9%); >3岁患儿以鸡蛋检出阳性率最高,分别为77.8%、69.9%,其次为牛奶,分别为61.9%、62.1%; ≤3岁患儿,以牛奶检出阳性率最高,分别为77.6%、76.2%,其次为鸡蛋,分别为56.5%、46.3%。多种食物不耐受阳性率从高到低依次为3种及以上、2种、1种。牛奶和鸡蛋是引起中重度食物不耐受的主要食物,也是同一病种多种食物不耐受的主要食物。结论 消化道、皮肤两种变应性疾病患儿与食物不耐受关系密切,学龄前后食物不耐受表现形式不同,这为减少食物不耐受疾病发生,指导喂养提供了科学依据。
Abstract:
Objective To investigate the distribution patterns and positive rate distribution of food intolerance in children before and after school age, and to provide scientific feeding basis for reducing the development of food intolerance. Methods Enzyme-linked immunosorbent assay(ELISA)was used to detect 14 kinds of common food intolerance-specific IgG antibodies in children with digestive tract and skin diseases before and after school age.The grades were analyzed and the degree of food intolerance was analyzed. Results Among the 1 626 children, the positive rate of 14 kinds of food intolerance-specific IgG antibodies was 88.0%. The positive rate of intolerance was similar in children with two diseases(88.2%, 86.9%).For children >3 years old,the positive rate of egg detection was the highest in 77.8% and 69.9%,respectively. Followed by milk,which were 61.9% and 62.1%.For children ≤3 years old,the highest positive rate was detected in milk,which were 77.6% and 76.2%, followed by eggs, which were 56.5% and 46.3%,respectively. The positive rates of various food intolerances were three or more, two, and one from high to low. Milk and eggs were the main foods that cause moderate to severe food intolerance, and were the main foods that were intolerant to multiple foods of the same disease. Conclusion Children with digestive tract and skin allergic diseases are closely related to food intolerance.The pattern of food intolerance before and after school age is different, which provides a scientific basis for reducing the occurrence of food intolerance and guiding feeding.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目:福建省自然科学基金资助项目(2016J01436)1 通信作者
更新日期/Last Update: 2019-12-25