[1]陈琼华 郑敬阳 张圳杰 林印涛 曾丽娥 林春燕 张 谭.婴幼儿反复喘息136例病因分析[J].福建医药杂志,2019,41(06):12-15.
　CHEN Qionghua,ZHENG Jingyang,ZHANG Zhenjie,et al.Etiological analysis of recurrent wheezing in 136 infants[J].FUJIAN MEDICAL JOURNAL,2019,41(06):12-15.
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婴幼儿反复喘息136例病因分析()
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《福建医药杂志》[ISSN:1002-2600/CN:35-1071/R]

卷:
41
期数:
2019年06期
页码:
12-15
栏目:
临床研究
出版日期:
2019-12-25

文章信息/Info

Title:
Etiological analysis of recurrent wheezing in 136 infants
文章编号:
1002-2600(2019)06-0012-04
作者:
陈琼华 郑敬阳 张圳杰 林印涛 曾丽娥 林春燕 张 谭
福建省泉州市儿童医院呼吸科(泉州 362000)
Author(s):
CHEN Qionghua; ZHENG Jingyang; ZHANG Zhenjie; LIN Yintao; ZENG Lie; LIN Chunyan; ZHANG Tan.
Department of Respiratory, Quanzhou Childrens Hospital, Quanzhou, Fujian 362000, China
关键词:
婴幼儿;  喘息;  病因
Keywords:
infant;  wheezing;  etiology
分类号:
R725.6
文献标志码:
B
摘要:
目的 分析婴幼儿反复喘息的病因。方法 收集患儿的一般资料、临床症状及体征、病原学、胸部CT 等影像学、免疫学进行分析,研究反复喘息的病因。结果 引起反复喘息的主要原因为:婴幼儿哮喘47例(34.6%)、感染62例(45.6%)、闭塞性细支气管炎4例(2.9%)、支气管肺发育不良7例(5.1%)、胃食管反流2例(1.5%),支气管内异物2例(1.5%),气道畸形9例(6.6%),心血管畸形2例(1.5%),免疫缺陷1例(0.7%)。感染相关喘息中有23例被检出合并现症感染,支原体感染达16.1%。哮喘预测指数(API)阳性者46例(34.6%)。106例胸部CT检查中90例为炎症改变,46例患儿支气管镜表现为气管支气管内膜炎为主。62例患儿考虑感染后喘息,但还应注意其他少见病因可能。结论 婴幼儿反复喘息大部分有因可寻,感染相关喘息和哮喘是导致婴幼儿反复喘息的常见原因,诊断应从常见病入手,但还应注意少见病可能,加强随访评估。
Abstract:
Objective To analyze the etiology of recurrent wheezing in infants.Methods The general information,clinical symptons and signs,etiology,chest CT and other imaging and immunology of the children were collected and analyzed to study the causes of recurrent wheezing.Results The main causes of recurrent wheezing were as follows: 47 infants with asthma(34.6%), 62 infants with infection(45.6%), 4 infants with bronchiolitis obliterans(2.9%), 7 infants with bronchopulmonary dysplasia(5.1%), 2 infants with gastroesophageal reflux(1.5%), 2 infants with intrabronchial foreign bodies(1.5%), 9 infants with airway malformation(6.6%), 2 infants with cardiovascular malformation(1.5%)and 1 case with immune deficiency(0.7%).Current infection was found in 23 cases of infection-related wheezing, with mycoplasma infection reaching 16.1%.Asthma predictive index(API)was positive in 46 cases(34.6%).Ninety cases demonstrated inflammation in the chest CT examination, while 46 cases showed endobronchitis under bronchoscopy.Post-infection wheezing was considered in 62 patients, while attention should be paid to the possibility of other rare causes.Conclusion The causes of recurrent wheezing infant can be found in most cases.Infection-related wheezing and asthma are common causes.Diagnosis should be started with common diseases,and the possibility of rare diseases cannot be ignored.Strengthened follow-up evaluation are needed.

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备注/Memo

备注/Memo:
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更新日期/Last Update: 2019-12-25