[1]王 薇 任 彦 付肖岩.内镜下金属钛夹联合肾上腺素注射治疗老年ANVUGIB的 临床研究[J].福建医药杂志,2019,41(04):9-12.
　WANG Wei,REN Yan,FU Xiaoyan.Clinical study of combination therapy of epinephrine injection with endoscopic hemoclip in the treatment of the elderly patients with acute non-variceal upper gastrointestinal bleeding[J].FUJIAN MEDICAL JOURNAL,2019,41(04):9-12.
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内镜下金属钛夹联合肾上腺素注射治疗老年ANVUGIB的 临床研究()
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《福建医药杂志》[ISSN:1002-2600/CN:35-1071/R]

卷:
41
期数:
2019年04期
页码:
9-12
栏目:
临床研究
出版日期:
2019-08-15

文章信息/Info

Title:
Clinical study of combination therapy of epinephrine injection with endoscopic hemoclip in the treatment of the elderly patients with acute non-variceal upper gastrointestinal bleeding
文章编号:
1002-2600(2019)04-0009-04
作者:
王 薇 任 彦 付肖岩
福建中医药大学附属第二人民医院消化内科(福州 350003)
Author(s):
WANG Wei;  REN Yan;  FU Xiaoyan
Department of Gastroenterology, the Second Affiliated Peoples Hospital,Fujian University of Traditional Chinese Medicine,Fuzhou, Fujian 350003,China
关键词:
上消化道出血;  金属钛夹;  肾上腺素;  止血;  老年患者
Keywords:
acute upper gastrointestinal bleeding;  hemoclip;  epinephrine;  hemostasis;  elderly patients
分类号:
R573.2
文献标志码:
B
摘要:
目的 观察内镜下金属钛夹联合肾上腺素注射治疗老年急性非静脉曲张性上消化 道出血(ANVUGIB)的临床效果。方法 收集2013年1月至2017年12月293例ANVUGIB患者临床资 料,其中,202例接受内镜下肾上腺素注射治疗(肾上腺素注射组),91例接受内镜下金属钛夹联 合肾上腺素注射治疗(联合治疗组)。评估两组初次止血率、再出血率、外科手术率、30天死 亡率和住院时间长短。结果 肾上腺素注射组和联合治疗组:初次止血率分别达到83.17%和 95.6%(P<0.05); 再出血率(14.85% vs 4.39%)和住院时间也有显著改变 (P<0.05); 外科手术率无显著改变,分别为5.45% vs 1.09%; 30天死亡率 相当(1.98% vs 1.09%); 均未发现明显的内镜治疗并发症。 结论 内镜下金属钛夹 联合肾上腺素注射治疗是一种止血效果显著且安全的方法。
Abstract:
Objective To validate the efficacy of endoscopic hemoclips in combination with epinephrine injection in the treatment of the elderly patients with Acute Non-variceal Upper Gastrointestinal Bleeding(ANVUGIB), and to compare the clinical outcomes between patients treated with such a combination therapy and those treated with epinephrine injection alone.Methods Between February 1st 2013 and December 31st 2017, a total of 293 elderly patients with ANVUGIB were enderwent endoscopic therapy.Among these, 202 patients received epinephrine injection therapy(epinephrine injection group)while 91 patients received combination therapy of epinephrine injection with endoscopic hemoclip(combined treatment group).Primary hemostasis rates, re-bleeding rates, surgical rate, 30 -day mortality and hospitalization time were evaluated in both groups.Results The initial hemostasis of patients in epinephrine and endoscopic hemoclip plus epinephrine achieved 83.17% and 95.6% respectively(P<0.05).We detected significant difference in rate of re-bleeding(14.85% vs 4.39%)and the hospitalization time also changed significantly(P<0.05).However,there was no significant difference in the proportions of patients who required surgery, 5.45% vs 1.09%, respectively.And mortality in 30d was equal (1.98% vs 1.09%)in the two groups.No obvious complications from endoscopic treatment were observed in either group.Conclusion Combination therapy of epinephrine injection with endoscopic hemoclip application is an effective and safe method.

参考文献/References:

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更新日期/Last Update: 2019-08-15