[1]陈迎月 郑 帆 傅月梅 高诚斌 高京华.七叶洋地黄双苷滴眼液及视觉训练对中高度近视LASIK术后 视功能恢复的疗效观察[J].福建医药杂志,2019,41(04):1-5.
　CHEN Yingyue,ZHENG Fan,FU Yuemei,et al.Clinical effect of esculin and digitalisglycosides eyes drops and visual training in recovering visual function of patients with medium and high myopia after LASIK[J].FUJIAN MEDICAL JOURNAL,2019,41(04):1-5.
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七叶洋地黄双苷滴眼液及视觉训练对中高度近视LASIK术后 视功能恢复的疗效观察()
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《福建医药杂志》[ISSN:1002-2600/CN:35-1071/R]

卷:
41
期数:
2019年04期
页码:
1-5
栏目:
临床研究
出版日期:
2019-08-15

文章信息/Info

Title:
Clinical effect of esculin and digitalisglycosides eyes drops and visual training in recovering visual function of patients with medium and high myopia after LASIK
文章编号:
1002-2600(2019)04-0001-05
作者:
陈迎月 郑 帆 傅月梅1 高诚斌 1 高京华1
厦门大学附属福州第二医院眼科(福州 350007)
Author(s):
CHEN Yingyue; ZHENG Fan; FU Yuemei; GAO Chengbin; GAO Jinghua
Department of Ophthalmology,the Affiliated Fuzhou Municipal Second Hospital of Xiamen University,Fuzhou,Fujian 350007,China
关键词:
准分子激光原位角膜磨镶术;  近视;  调节;  七叶洋地黄双苷滴眼液;  视觉训练
Keywords:
laser in stiu keratomileusis;  myopia;  accommodation;  esculin and digitalisglycosides eyes drops;  visual training
分类号:
R779.63
文献标志码:
A
摘要:
目的 通过观察七叶洋地黄双苷滴眼液及视觉训练对中高度近视激光原位角膜磨 镶术(LASIK)术后视功能恢复疗效,探讨LASIK术后改善视疲劳的有效方法。方法 前瞻、随机 选取飞秒激光LASIK手术的中高度近视患者,根据治疗方式分为对照、药物及药物训练组各40 例(80眼,中高度近视例数各半)。对照组常规药物治疗,药物组常规药物加七叶洋地黄双苷滴 眼液治疗,药物训练组常规药物加七叶洋地黄双苷滴眼液及个性化视觉训练。七叶洋地黄双 苷滴眼液治疗及个性化视觉训练于术后1周开始。分别进行术前,术后1周及1、3个月的视疲 劳问卷评分和视功能检查。结果 术后1周视疲劳问卷评分分数增加,调节反应有所超前,单眼 调节幅度及正/负相对调节下降。术后1个月视疲劳问卷调查评分分数开始下降; 调节反应逐 渐恢复正常; 单眼调节幅度恢复幅度药物及药物训练组好于对照组(P<0.05); 正 相对调节药物及药物训练组比术前好转,治疗效果药物训练组好于药物组 (P<0.05); 负相对调节药物训练组恢复快于药物及对照组; 单眼调节灵敏度各组 均比术前好转,药物训练组好于药物及对照组(P<0.05)。术后3个月单眼调节幅度 恢复幅度药物训练组好于药物组(P<0.05)。结论 七叶洋地黄双苷滴眼液能恢复 和改善LASIK术后患者的眼部调节功能,而结合个性化的视觉训练能缩短恢复调节功能时间和 增加改善调节功能效果。
Abstract:
Objective To evaluate the effective methods of improving visual fatigue after laser in stiu keratomileusis(LASIK)by observing the effect of esculin and digitalisglycosides eyes drops and visual training in recovering visual function of patients with medium and high myopia after LASIK.Methods The patients with medium and high myopia treated by LASIK with Femtosecond Laser were prospectively and randomly divided into control group,drug group and drug training group.Each group contained 40 patients(80 eyes),which medium and high myopia patients were even.Control group was given routine drug,while esculin and digitalisglycosides eyes drops was added in Drug group.Drug training group added personalized visual training in addition to the treatment above.Different treatments started at 1 week after surgery.Visual fatigue questionnaire score and visual function were measured before surgery,1 week,1 month and 3 months after surgery.Results After surgery visual fatigue questionnaire score increased, adjusting reaction advanced, the monocular accommodative amplitude and positive/ negative relative accommodation descended after 1 week.But visual fatigue questionnaire score began to decline and adjusting reaction returned to normal gradually after 1 month.The recovery changes of the monocular accommodative amplitude of drug group and drug training group were significantly larger than that of control group(P<0.05).The positive relative accommodation of drug group and drug training group were better than that of before surgery.The changes of drug training group were significantly larger than that of drug group(P<0.05).The negative relative accommodation of drug training group recovered faster than the other groups.However the monocular accommodative sensitivity were all better than before.The effect of drug training group was significantly better than the others(P<0.05).After 3 months,the recovery changes of the monocular accommodative amplitude of drug training group was significantly better than that of drug group (P<0.05).Conclusion Esculin and digitalisglycosides eyes drops can recover and improve the patients accommodative functions.Furthermore personalized visual training can shorten the recovery time and improve the effect.

参考文献/References:

[1] 陈世豪,吕帆,王勤美,等.LASIK对近视眼调节功能的影响及其临床意义[J].眼视光学杂 志,2000,2(1):26-29.
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[5] 吴鲁华,李耀宇,翟国光,等.七叶洋地黄双苷滴眼液对于LASIK术后眼调节力的影响 [J].中国中医眼科杂志,2012,22(4):251-254.
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备注/Memo

备注/Memo:
基金项目:福州市卫生计生科技计划中青年科研项目(2017-S-wq3) 1 福州眼科医院
更新日期/Last Update: 2019-08-15