[1]刁雪红,申艳,詹嘉,等.超微血管成像技术对评估类风湿性关节炎活动性的价值[J].福建医药杂志,2022,44(01):5-8.
　DIAO Xuehong,SHEN Yan,ZHAN Jia,et al.Value of superb micro-vascular imaging in the assessment of rheumatoid arthritis activity[J].FUJIAN MEDICAL JOURNAL,2022,44(01):5-8.
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超微血管成像技术对评估类风湿性关节炎活动性的价值()
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《福建医药杂志》[ISSN:1002-2600/CN:35-1071/R]

卷:
44
期数:
2022年01期
页码:
5-8
栏目:
临床研究
出版日期:
2022-02-15

文章信息/Info

Title:
Value of superb micro-vascular imaging in the assessment of rheumatoid arthritis activity
文章编号:
1002-2600(2022)01-0005-04
作者:
刁雪红; 申艳1; 詹嘉; 陈林; 蔡剑飞1; 方靓; 张音佳1; 陈悦2
复旦大学附属华东医院超声科(上海200040)
Author(s):
DIAO Xuehong;  SHEN Yan;  ZHAN Jia;  CHEN Lin;  CAI Jianfei;  FANG Liang; ZHANG YinJia;  CHEN Yue
Department of Ultrasound，Huadong Hospital of Fudan University, Shanghai 200040, China
关键词:
类风湿性关节炎; 超微血管成像技术; 能量多普勒超声; 超声造影; 滑膜血流
Keywords:
RF;  SMI;  PDUS;  CEUS;  synovial blood flow
分类号:
R445.1
文献标志码:
B
摘要:
目的 对比研究超微血管成像技术(SMI)、 能量多普勒超声(PDUS) 及超声造影(CEUS)在判断类风湿性关节炎活动性的价值。方法 对50例RA活动期患者进行超声检查，观察SMI、PDUS、CEUS血流模式对最厚处滑膜血流的显示率和滑膜血流分级的差异，并与DAS28、类风湿因子(RF)、 C反应蛋白(CRP)、 血沉(ESR) 进行相关性分析，评估SMI对RA患者关节炎症活动性的临床应用价值。结果 在RA患者中，CEUS、SMI、PDUS对滑膜血流的显示率分别为92%、88%、76%，SMI与CEUS较PDUS可以检测出更多关节的滑膜血流，而SMI对关节滑膜血流的显示与CEUS无明显差异(P=0.159);通过评估滑膜血流分级发现，SMI与CEUS,较PDUS，血流分级更高。CEUS、SMI及PDUS的滑膜血流分级与ESR、CRP、DAS28 均星正相关。结论 SMI在观察RA患者增生滑膜血流信号方面优于PDUS,可更准确地评估RA患者的疾病活动性。
Abstract:
Objective To compare the value of superb microvascular imaging (SMI), power doppler imaging (PDUS) and contrast enhanced ultrasound (CEUS) in patients with activity of rheumatoid arthritis (RA). Methods The thickest synovium of 50 patients underwent superb SMI，PDUS and CEUS. The display rate of synovial blood flow and synovial blood flow classification were observed. The correlation between the DAS28，rheumatoid factor (RF), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) and SMI were analyzed to evaluate the clinical application value of SMI in activity of RA. Results The blood flow detectable rate of CEUS, SMI and PDUS were 92%，88% and 76% respectively, and there was no significant difference in the detection of synovial blood flow between the SMI and CEUS (P=0.159). SMI and CEUS could detect more synovial blood flow, it had higher vascularity classification than PDUS. CEUS, SMI and PDUS were in good agreement with CRP，ESR and DAS28. Conclusion SMI is more sensitive in detecting synovial inflammation than PDUS in patients with RA. SMI can be a potentially useful imaging modality for accurately diagnosing and monitoring the disease activity of RA.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目:上海市卫生和计划生育委员会科研课题(20174Y0127)
1 免疫风湿科; 2 通信作者，Email:ultrasound_chen@126.com
更新日期/Last Update: 2022-02-15