[1]程 盛,林 宁,唐 力.无被膜接触的甲状腺乳头状微小癌中央区淋巴结转移的危险因素[J].福建医药杂志,2021,43(05):1-5.
　CHENG Sheng,LIN Ning,TANG Li.Risk factors for central lymph node metastasis of papillary thyroid microcarcinoma without capsule contact[J].FUJIAN MEDICAL JOURNAL,2021,43(05):1-5.
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无被膜接触的甲状腺乳头状微小癌中央区淋巴结转移的危险因素()
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《福建医药杂志》[ISSN:1002-2600/CN:35-1071/R]

卷:
43
期数:
2021年05期
页码:
1-5
栏目:
临床研究
出版日期:
2021-10-15

文章信息/Info

Title:
Risk factors for central lymph node metastasis of papillary thyroid microcarcinoma without capsule contact
文章编号:
1002-2600(2021)05-0001-05
作者:
程 盛; 林 宁1; 唐 力
福建医科大学省立临床医学院 福建省立医院超声科(福州 350001)
Author(s):
CHENG Sheng; LIN Ning; TANG Li
Department of Ultrasound, Fujian Provincial Hospital,Provincial Clinical Me-dical College of Fujian Medical University,Fuzhou,Fujian 350001,China
关键词:
甲状腺乳头状微小癌;  甲状腺被膜;  距离;  中央区淋巴结转移
Keywords:
papillary thyroid microcarcinoma;  capsule of thyroid;  distance;  central lymph node metastasis
分类号:
R445.1
文献标志码:
A
摘要:
目的 探讨无甲状腺被膜接触的甲状腺乳头状微小癌(papillary thyroid microcarcinoma,PTMC)中央区淋巴结转移(central lymph node metastasis,CLNM)的危险因素。方法 回顾性分析354例于我院手术且术后病理证实为单灶性PTMC者的术前超声和临床病理特征与CLNM的关系。结果 单因素分析显示,性别,年龄,癌灶的左右径,前后径,上下径,体积,边缘,微钙化,距内、外缘距离均与CLNM显著相关。多因素分析显示,男性,年龄<46岁,上下径≥6.1 mm,微钙化,边缘不光整,癌灶距甲状腺内侧缘≤2.4 mm和距外侧缘≥8.0 mm是CLNM的独立危险因素,其中微钙化的OR值最高(10.224)。结论 男性,年龄<46岁,上下径≥6.1 mm,微钙化,边缘不光整,癌灶距甲状腺内侧缘≤2.4 mm和距外侧缘≥8.0 mm是无被膜接触PTMC发生CLNM的独立危险因素,其中微钙化风险值最大。
Abstract:
Objective To explore the risk factors of central lymph node metastasis(CLNM)of papillary thyroid microcarcinoma(PTMC)without thyroid capsule contact.Methods A retrospective analysis of the relationship between preoperative ultrasound and clinicopathological features of 354 patients who were operated in our hospital and proved to be unifocal PTMC by pathologyand CLNM.Results Univariate analysis showed that gender,age,transverse diameter(TD),anteroposterior diameter(APD),sagittal diameter(SD),volume,distance to inner-capsule(DTI),distance to outer-capsule(DTO),margin,and microcalcification were all significantly related to CLNM.Multivariate analysis showed that male,age<46 years,SD≥6.1 mm,microcalcification,ill-defined margin,DTI≤2.4 mm and DTO≥8.0 mm were independent risk factors for CLNM,the OR value of microcalcification was the highest(10.224).Conclusion Male,age<46 years,SD≥6.1 mm,microcalcification,ill-defined margin,DTI≤2.4 mm and DTO≥8.0 mm are independent risk factors for CLNM in PTMC without capsule contact,and microcalcification has the greatest risk.

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备注/Memo

备注/Memo:
基金项目:福建省财政厅2020年卫生健康省级专项补助资金(006019200305)
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更新日期/Last Update: 2021-10-15