[1]何金兰.胰岛素泵在2型糖尿病伴颈动脉粥样硬化患者中的应用效果[J].福建医药杂志,2021,43(03):19-22.
　HE Jinlan.Application effect of insulin pump in patients with type 2 diabetes mellitus complicated with carotid atherosclerosis[J].FUJIAN MEDICAL JOURNAL,2021,43(03):19-22.
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胰岛素泵在2型糖尿病伴颈动脉粥样硬化患者中的应用效果()
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《福建医药杂志》[ISSN:1002-2600/CN:35-1071/R]

卷:
43
期数:
2021年03期
页码:
19-22
栏目:
临床研究
出版日期:
2021-06-15

文章信息/Info

Title:
Application effect of insulin pump in patients with type 2 diabetes mellitus complicated with carotid atherosclerosis
文章编号:
1002-2600(2021)03-0019-04
作者:
何金兰
福建省龙岩人民医院内分泌科(龙岩 364000)
Author(s):
HE Jinlan
Department of Endocrinology, Longyan People’s Hospital of Fujian, Longyan, Fujian 364000, China
关键词:
胰岛素泵;  传统皮下注射;  2型糖尿病;  颈动脉粥样硬化
Keywords:
insulin pump;  traditional subcutaneous injection;  type 2 diabetes mellitus;  carotid atherosclerosis
分类号:
R587.2
文献标志码:
B
摘要:
目的 研究胰岛素泵在2型糖尿病(T2DM)伴颈动脉粥样硬化患者中的应用效果。方法 选取192例确诊为T2DM伴颈动脉粥样硬化患者,按照随机数字表法分为研究组和对照组各96例。对照组使用传统皮下注射给药方式治疗,每日三餐前注射给药; 研究组采用胰岛素泵持续注射给药治疗。比较两组患者治疗前及治疗2个月后糖代谢指标(FBG、P2hBG、GHbA1C)、脂代谢指标(HDL-C、LDL-C、TG、TC)、FINS情况。观察并统计两组患者治疗过程中低血糖发生情况。结果 治疗2个月后,两组患者FBG、P2hBG、GHbA1C、LDL-C、TG、TC、FINS均较治疗前明显降低(P<0.05),且研究组明显低于同期对照组(P<0.05); 两组患者HDL-C均较治疗前明显升高(P<0.05),且研究组明显高于同期对照组(P<0.05); 治疗过程中研究组患者低血糖发生次数明显小于对照组(P<0.05)。结论 胰岛素泵治疗T2DM伴颈动脉粥样硬化患者可明显且安全降低其血糖血脂水平,对比传统皮下注射治疗效果更显著,对改善其预后具有积极作用。
Abstract:
Objective To study the application effect of insulin pump in patients with type 2 diabetes mellitus(T2DM)complicated with carotid atherosclerosis.Methods One hundred and ninety-two patients diagnosed with T2DM complicated with carotid atherosclerosis were selected and divided into study group and control group with 96 cases in each group according to the random number table method.Control group was treated with traditional subcutaneous injection, and was injected before three meals a day.Study group was treated with continuous injection of insulin pump.The glucose metabolism indicators(FBG, P2hBG, GHbA1C), lipid metabolism indicators(HDL-C, LDL-C, TG, TC)and FINS were compared between the two groups of patients before treatment and after 2 months of treatment.The occurrence of hypoglycemia was observed and counted in the two groups of patients during treatment.Results After 2 months of treatment, the levels of FBG, P2hBG, GHbA1C, LDL-C, TG, TC and FINS of the two groups were significantly decreased compared to previous treatment(P<0.05), and the levels of study group were significantly lower than those of control group during the same period(P<0.05).The HDL-C level of the two groups of patients was obviously increased compared with that before treatment(P<0.05), and the level of study group was significantly higher than that of control group during the same period(P<0.05).The frequency of hypoglycemia occurrence in study group was significantly less than that in control group during treatment(P<0.05).Conclusion Insulin pump for the treatment of T2DM patients complicated with carotid atherosclerosis can significantly and safely reduce the levels of blood glucose and blood lipids.Compared to traditional subcutaneous injection, it has a more significant effect and has a positive effect on improving the prognosis.

参考文献/References:

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更新日期/Last Update: 2021-06-15