[1]吴 超 潘小滨 石松长 林兴盛.高渗盐水和甘露醇治疗重型颅脑损伤的效果[J].福建医药杂志,2019,41(03):26-28.
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高渗盐水和甘露醇治疗重型颅脑损伤的效果()
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《福建医药杂志》[ISSN:1002-2600/CN:35-1071/R]

卷:
41
期数:
2019年03期
页码:
26-28
栏目:
临床研究
出版日期:
2019-02-20

文章信息/Info

文章编号:
1002-2600(2019)03-0026-03
作者:
吴 超 潘小滨 石松长 林兴盛
福建省立医院南院重症医学一科(福州 350028)
关键词:
高渗盐水 甘露醇 颅内压 神经元特异性烯醇化酶 NSE
分类号:
R651.15
文献标志码:
B
摘要:
目的 比较高渗盐水和甘露醇治疗重型颅脑损伤的效果。方法 回顾性分析我院收治 的42例行标准去骨瓣减压+颅内血肿清除术的重型颅脑损伤患者的临床资料。其中术后仅使用高 渗盐水治疗的重症颅脑损伤患者21例为高渗盐水组,术后仅使用甘露醇治疗的重型颅脑损伤患者 21例为甘露醇组。比较两组患者的瞳孔异常发生率、2周内死亡发生率、ICP监测天数、ICU住院 天数等一般情况,颅内压负荷累积率、每日颅内压负荷时间,入院当天、第3天、第5天、第7天血 清神经元特异性烯醇化酶(NSE)水平。结果 治疗后,高渗盐水组颅内压负荷累积率,每日颅内压 负荷时间,ICU住院天数,入院第3天、第5天、第7天各时间点血清NSE水平均低于甘露醇组,差异 均有统计学意义(P<0.05)。结论 高渗盐水治疗重型颅脑损伤比甘露醇更有效。

参考文献/References:

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更新日期/Last Update: 2019-02-20