[1]杨秀娟,姚军.不同浓度的赤藓糖醇对变异链球菌生物膜结构的影响[J].福建医药杂志,2023,45(03):109-112.
　YANG Xiujuan,YAO Jun.Effects of erythritol at different concentrations on the biofilm structure of streptococcus mutans[J].FUJIAN MEDICAL JOURNAL,2023,45(03):109-112.
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不同浓度的赤藓糖醇对变异链球菌生物膜结构的影响()
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《福建医药杂志》[ISSN:1002-2600/CN:35-1071/R]

卷:
45
期数:
2023年03期
页码:
109-112
栏目:
基础研究
出版日期:
2023-06-15

文章信息/Info

Title:
Effects of erythritol at different concentrations on the biofilm structure of streptococcus mutans
文章编号:
1002-2600(2023)03-0109-04
作者:
杨秀娟; 姚军
福建医科大学附属口腔医院儿童牙科(福州 350002)
Author(s):
YANG Xiujuan;  YAO Jun
Department of Pediatric Dentistry, Affiliated Stomatological Hospital of Fujian Medical University, Fuzhou, Fujian 350002, China
关键词:
赤藓糖醇;  变异链球菌;  生物膜
Keywords:
erythritol;  streptococcus mutans;  biofilm
分类号:
R780.1
文献标志码:
B
摘要:
目的 探讨不同浓度的赤藓糖醇对变异链球菌生物膜结构的影响。方法 采用激光共聚焦显微镜结合死菌与活菌荧光染色技术,对比不同浓度的赤藓糖醇对变异链球菌生物膜结构的影响。结果 随着赤藓糖醇浓度的增加,变异链球菌生物膜各层活菌百分比减少,厚度变薄,细菌密度降低,且差异均有统计学意义(P<0.05)。结论 赤藓糖醇对变异链球菌有抑制作用,作用随浓度增加而增强。
Abstract:
Objective To compare the effects of erythritol at different concentrations on the biofilm structure of streptococcus mutans. Methods The effects of different concentrations of erythritol on the biofilm structure of streptococcus mutans were compared by CLSM combined with fluorescence staining of dead bacteria and live bacteria. Results With the increase of erythritol concentration,the percentage of viable bacteria in each biofilm layer of streptococcus mutans decreased, the thickness became thinner, the bacterial density decreased, and the differences were significant(P<0.05). Conclusion Erythritol has an inhibitory effect on streptococcus mutans, and the effect increases with the increase of erythritol concentration.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目:福建省医学创新课题(2017-CX-33)
更新日期/Last Update: 2023-06-15