[1]李双齐,李航,张劲帆,等.乳房象限切除联合胸背动脉穿支皮瓣在T2期乳腺癌保乳重建中的应用[J].福建医药杂志,2023,45(03):9-12.
 LI Shuangqi,LI Hang,ZHANG Jinfan,et al.Application of quadrant mastectomy combined with thoracodorsal artery perforator flap inbreast-conserving reconstruction of T2 breast cancer[J].FUJIAN MEDICAL JOURNAL,2023,45(03):9-12.
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乳房象限切除联合胸背动脉穿支皮瓣在T2期乳腺癌保乳重建中的应用()
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《福建医药杂志》[ISSN:1002-2600/CN:35-1071/R]

卷:
45
期数:
2023年03期
页码:
9-12
栏目:
临床研究
出版日期:
2023-06-15

文章信息/Info

Title:
Application of quadrant mastectomy combined with thoracodorsal artery perforator flap inbreast-conserving reconstruction of T2 breast cancer
文章编号:
1002-2600(2023)03-0009-04
作者:
李双齐李航张劲帆林力生
莆田学院附属医院乳腺外科(莆田 351100)
Author(s):
LI Shuangqi LI Hang ZHANG Jinfan LIN Lisheng
Department of Breast Surgery, Affiliated Hospital of Putian University, Putian, Fujian 351100, China
关键词:
乳房象限切除 胸背动脉穿支皮瓣 保乳手术
Keywords:
quadrant breast resection thoracodorsal artery perforator flap breast-conserving surgery
分类号:
R737.9
文献标志码:
B
摘要:
目的 探讨乳房象限切除联合胸背动脉穿支皮瓣在T2期乳腺癌保乳治疗中的安全性及应用效果。方法 收集我院2019年1月至2020年12月T2期乳腺癌患者26例,通过乳房象限切除术进行保乳手术,并联合胸背动脉穿支皮瓣修复保乳后乳房缺损,观察疗效及并发症的发生情况。结果 全组均顺利完成手术,手术时间为(172.46±24.51)min,所有患者保乳切缘均为阴性,住院时间为(5.23±0.97)d。术后有1例受区脂肪液化,经创面处理后愈合良好,并发症发生率为3.85%。术后随访18~36个月,中位随访时间26个月,所有患者均未发生局部复发或远处转移。乳房外形术后恢复较好,术后12个月乳房满意度Breast-Q评分60.96±13.14,与术前乳房满意度Breast-Q评分61.65±12.39比较,差异无统计学意义(P>0.05)。结论 乳房象限切除联合胸背动脉穿支皮瓣,切缘阳性率和局部复发率低,术后并发症少,术后乳房外形满意度高,是T2期乳腺癌保乳手术的良好选择,该技术是安全、有效的。
Abstract:
Objective To investigate the safety and efficacy of quadrant mastectomy combined with thoracodorsal artery perforator flap in breast conserving treatment of T2 stage breast cancer. Methods From January 2019 to December 2020, 26 patients with T2 stage breast cancer in our hospital were collected. Breast conserving surgery was performed by quadrant mastectomy, and the breast defect after breast conserving was repaired by combining the thoracodorsal artery perforator flap. The efficacy and complications were observed. Results All patients underwent surgery successfully. The operation time was(172.46±24.51)min. All the patients had negative breast preservation margins.The hospitalization time was(5.23±0.97)d. There was no malformation and seroma in the donor area. After the operation, one patient developed fat liquefaction in the recipient area, and the wound healed well after treatment. The complication rate was 3.85%. All patients were followed up for 18-36 months, with a median follow-up of 26 months. No local recurrence or distant metastasis occurred.The appearance of the breast recovered well after operation, the Breast Satisfaction Break-Q score in 12 months after operation was 60.96±13.14, and the Breast Satisfaction Break-Q score before operation was 61.65±12.39, the difference was not statistically significant(P>0.05). Conclusion Quadrant mastectomy combined with thoracodorsal artery perforator flap is a good choice for breast conserving surgery for stage T2 breast cancer, with low positive rate of incision margin and local recurrence rate, few postoperative complications, and high satisfaction of postoperative breast shape. This technique is safe and effective.

参考文献/References:

[1] Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin, 2018, 68(6): 394-424.
[2] 张雪,董晓平,管雅喆,等.女性乳腺癌流行病学趋势及危险因素研究进展[J].肿瘤防治研究,2021,48(1):87-92.
[3] 邹天宁,唐一吟,张季,等.乳腺癌保乳术局部缺损即刻整形修复的临床研究[J].现代肿瘤医学,2011,45(21):143-144.
[4] Singletary S E.Breast cancer management:the road to today [J].Cancer,2018,113(7 Suppl):1844-1849.
[5] Sinnadurai S, Kwong A, Hartman M, et al. Breast-conserving surgery versus mastectomy in young women with breast cancer in Asian settings[J]. BJS Open,2018,3(1):48-55.
[6] Jin S, Xu B, Shan M, et al. Clinical significance of oncoplastic breast-conserving surgery and application of volumedisplace-ment technique[J]. Ann Plast Surg,2021,86(2):233-236.
[7] Munhoz A M,Montag E,Filassi J R,et al. Current approaches to managing partial breast defects: the role of conservative breast surgery reconstruction [J]. Anticancer Res,2014,34(3):1099-1114.
[8] Zhang Y X, Messmer C, Pang F K, et al. A novel design of the multilobed latissimus dorsi myocutaneous fl ap to achieve primary donor-site closure in the reconstruction of large defects[J]. Plast Reconstr Surg, 2013,131(5): 752e-758e.
[9] CHA H G, KANG S G, SHIN H S, et al. Does fibrin sealant reduce seroma after immediate breast reconstruction utilizing a latissimus dorsi myocutaneous flap[J]. Arch Plast Surg, 2012, 39(5): 504-508.
[10] Dast S, Berna P, Qassemyar Q, et al. A new option for autologous anterior chest wall reconstruction: the composite thoracodorsal artery perforator flap [J]. Ann Thorac Surg,2012,93(3):e67-e69.
[11] Sjøberg T, Mercer J B, Weum S, et al. The value of dynamic infrared thermography in pedicled thoracodorsal artery perfora-tor flap surgery[J]. Plast Reconstr Surg Glob Open,2020,8(7):e2799.
[12] Homsy C, Theunissen T, Sadeghi A. The thoracodorsal artery perforator flap: A powerful tool in breast reconstruction[J].Plast Reconstr Surg,2022,150(4):755-761.
[13] Zhang P H,Lu C L,Long J H,et al. Improved latissimus dorsi flap free grafting based on perforator flap conception for repairing soft tissue defects in the lower extremity[J].J Clin Rehab Tissue Eng Res,2010,14(31): 5873.
[14] Homsy C, Theunissen T, Sadeghi A. The thoracodorsal artery perforator flap: A powerful tool in breast reconstruction[J].Plast Reconstr Surg,2022,150(4):755-761

备注/Memo

备注/Memo:
基金项目:福建省自然科学基金资助项目(2019J01586)
更新日期/Last Update: 2023-06-15