[1]郭鹊晖 许 荣 林 晴 苏林丘 林秀青.经阴道三维超声多普勒评估复发性流产患者子宫内膜容受性的研究[J].福建医药杂志,2020,42(06):5-9.
　GUO Quehui,XU Rong,LIN Qing,et al.Evaluation of endometrial receptivity in patients with RSA by three-dimensional transvaginal ultrasound doppler[J].FUJIAN MEDICAL JOURNAL,2020,42(06):5-9.
点击复制

经阴道三维超声多普勒评估复发性流产患者子宫内膜容受性的研究()
分享到：

《福建医药杂志》[ISSN:1002-2600/CN:35-1071/R]

卷:
42
期数:
2020年06期
页码:
5-9
栏目:
临床研究
出版日期:
2020-12-15

文章信息/Info

Title:
Evaluation of endometrial receptivity in patients with RSA by three-dimensional transvaginal ultrasound doppler
文章编号:
1002-2600(2020)06-0005-05
作者:
郭鹊晖 许 荣 林 晴 苏林丘 林秀青1
福建中医药大学附属第二人民医院超声科(福州 350003)
Author(s):
GUO Quehui; XU Rong; LIN Qing; SU Linqiu; LIN Xiuqing.
Department of Ultrasound,the Second Affiliated Hospital of Fujian Traditional Chinese Medical University,Fuzhou,Fujian 350003,China
关键词:
经阴道三维超声多普勒;  复发性流产;  子宫内膜容受性
Keywords:
three-dimensional transvaginal ultrasound doppler;  recurrent abortion;  endometrial receptivity
分类号:
R445.1
文献标志码:
B
摘要:
目的 探讨经阴道三维超声多普勒(three-dimensional transvaginal ultrasound doppler, 3D-TVUD)技术在评估不明原因复发性流产(recurrent spontaneous abortion,RSA)患者子宫内膜容受性(endometrial receptivity,ER)中的临床应用价值。方法 收集到我院就诊的32例RSA患者及30例对照组,比较种植窗期两组患者子宫动脉及螺旋动脉血流频谱参数、子宫内膜厚度、类型、容积和血管化血流参数如血管形成指数(VI)、血流指数(FI)、血管形成-血流指数(VFI)等各项参数的差异。结果 RSA患者子宫动脉及螺旋动脉血流阻力指数(RI)、搏动指数(PI)均高于对照组,差异有统计学意义(P<0.05); RSA患者A型内膜数、子宫内膜厚度、容积、血管化血流参数(VI、FI、VFI)均小于对照组,差异有统计学意义(P<0.05); 而子宫动脉收缩期峰值流速(Vmax)两组间差异无统计学意义(P>0.05)。结论 3D-TVUD有助于评估不明原因RSA 患者子宫内膜容受性,其参数可为临床诊断和疗效评估提供参考。
Abstract:
Objective To investigate the clinical value of three-dimensional transvaginal ultrasound doppler technique in detecting endometrial receptivity related ultrasound parameters in patients with unexplained recurrent abortion.Methods Thirty-two patients with RSA and thirty controls in our hospital were collected, and the differences of uterine artery and spiral artery blood flow spectrum parameters, endometrial thickness, a type, volume and vascularization blood flow parameters(VI, FI and VFI)in the two groups during the implantation window period were compared.Results The RI and PI of the uterine artery and spiral artery in patients with RSA were higher than that in control group, and the differences were statistically significant.The number of type A endometrium, endometrial thickness, volume, and vascularization parameters(VI, FI, VFI)of patients with RSA were all lower than those of the control group, and the differences were statistically significant.There was no significant statistical difference in uterine artery velocity between two groups.Conclusion 3D-TVUD is helpful for the assessment of endometrial receptivity in patients with unexplained RSA, and its parameters can provide reference for clinical diagnosis and efficacy evaluation.

参考文献/References:

[1] 谢幸,苟文丽.妇产科学[M].第8版.北京:人民卫生出版社,2014,10(8):49.
[2] 刘慧,田葱,马明霞.经阴道超声在AIH- IUI中对子宫内膜容受性的应用价值[J].甘肃医药,2019,38,(1):38-39.
[3] Liang J, Wang S, Wang Z.Role of microRNAs in embryo implantation[J].Reprod Biol Endocrinol,2017,15(1):90.
[4] 邢俊,周建军,王俊霞,等.宫腔灌注HCG对反复种植失败及复发性流产患者外周血Treg的影响[J].南京医科大学学报:自然科学版,2016,36(12):1443-1445.
[5] 姚绚,杨正望.浅谈雌激素受体表达与 PCOS 患者子宫内膜容受性的关系[J].当代医药论丛,2013,11(9):32-34.
[6] 隋晓倩,于德钦,张冬梅.子宫内膜容受性各相关标志物研究进展[J].生殖与避孕, 2015,35(3):185-190.
[7] Ahmadi F,Akhbari F,Zamani M,et al.Value of endometrial echopattern at HCG administration day in predicting IVF outcome[J].Arch Iran Med,2017,20(2):101-104.
[8] Wang L,Qiao J,Li R,et al.Role of endometrial blood flow assessment with color doppler energy in predicting pregnancy outcome of IVF-ET cycles[J].Chinese Journal of Minimally Invasive Surgery,2010,8(1):122.
[9] Kim A,Jung H,Choi W J,et al.Detection of endometrial and subendometrial vasculature on the day of embryo transfer and prediction of pregnancy during fresh invitro fertilization cycles[J].Taiwanese Journal of Obstetrics and Gynecology,2014,53(3):360-365.
[10] Kasius A,Smit J G,Torrance H L,et al.Endometrial thickness and pregnancy rates after IVF:a systematic review and meta-analysis[J].Human Reproduction Update,2014,20(4):530-541.
[11] 贺方方,丁利军,朱颖春,等.子宫内膜厚度和体积对体外受精胚胎移植临床结局的预测作用[J].中华妇幼临床医学杂志:电子版,2015,11(05):570-573.
[12] 程军,范瑾,吴爱华,等.超声在复发性自然流产女性中对子宫内膜的诊断效果及血流动力学研究[J].中国社区医师, 2016,32(30):130-131.
[13] 王锦惠,于子芳,闫芳,等.经阴道二维及三维超声对体外受精-胚胎移植子宫内膜容受性的评估价值[J].中华医学超声杂志:电子版,2015,12(4):319-324.
[14] 钟华,唐至立.超声评价卵巢反应性和子宫内膜容受性与 IVF-ET 妊娠结局关系探讨[J].中外医学研究,2017,15(9):52 -53.
[15] Sardana D,Upadhyay A J,Deepika K,et al.Correlation of subendometrial endometrial blood flow assessment by two-dimensional power Doppler with pregnancy outcome in frozen-thawed embryotransfer cycles[J].J Hum Reprod Sci, 2014,7(2):130-135.
[16] 杨丹,杨洋,姚秀芬.超声技术对子宫内膜容受性与复发性流产患者妊娠结局的相关性研究[J].西藏医药,2018,39(4):30-32.
[17] 周秀萍,赵雅萍,王启亮,等.经阴道三维能量多普勒血流显像超声监测IVF-ET中子宫内膜参数评估子宫内膜容受性[J].浙江医学, 2019, 41(10):87-90.
[18] Zhang T J, He Y Q, Wang Y, et al.The role of three-dimensional power doppler ultrasound parameters measured on HCG day in the prediction of pregnancy during in vitro fertilization treatment [J].Eur J Obstet Gynecol Reprod Biol,2016,203:66-71.
[19] 焦岩,水旭娟,余彩茶,等.超声多模态评分在复发性自然流产患者子宫内膜容受性评价中的应用研究[J].中国全科医学, 2020,23(3):299-304.

备注/Memo

备注/Memo:
基金项目:福建省教育厅中青年教师教育科研项目(科技类)(JT180239)1 通信作者,Email:fjfzlxq@126.com
更新日期/Last Update: 1900-01-01