[1]林晓鸿 郭如清 李冰冰 邱阿春.重度与非重度阻塞性睡眠呼吸暂停低通气综合征217例危险因素分析[J].福建医药杂志,2020,42(05):48-50.
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重度与非重度阻塞性睡眠呼吸暂停低通气综合征217例危险因素分析()
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《福建医药杂志》[ISSN:1002-2600/CN:35-1071/R]

卷:
42
期数:
2020年05期
页码:
48-50
栏目:
临床研究
出版日期:
2020-10-20

文章信息/Info

文章编号:
1002-2600(2020)05-0048-04
作者:
林晓鸿 郭如清 李冰冰 邱阿春
福建省立医院呼吸与危重症医学科(福州 350001)
关键词:
阻塞性睡眠呼吸暂停 便携式睡眠呼吸监测 危险因素
分类号:
R563
文献标志码:
B
摘要:
目的 探讨基于便携式睡眠呼吸监测的重度与非重度阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)患者的危险因素。方法 选择我院睡眠医学中心的OSAHS患者217例,对其行夜间便携式睡眠呼吸监测,以及爱泼沃斯嗜睡量表(epworth sleepiness scale,ESS)评估,计算身体质量指数(BMI)等指标,根据睡眠呼吸暂停低通气指数(apnea-hypopnea index,AHI),将阻塞性睡眠呼吸暂停低通气综合征分为重度组(AHI>30次/h)99例与非重度组(AHI≤30次/h)118例,观察并分析危险因素。结果 与非重度OSAHS组比较,重度OSAHS组男性患病率更高(86.9% vs 67.8%; χ2=10.892,P=0.001)、ESS得分更高(9.00分 vs 6.00分; Z=-4.122,P<0.001)、存在日间嗜睡人数更多(47.5% vs 28.8%; χ2=8.014,P=0.005)、BMI更高(29.40 kg/m2 vs 26.16 kg/m2; Z=-5.538,P<0.001)、超重或肥胖人数更多(92.9% vs 75.4%; χ2=11.922,P=0.001)。多因素logistic回归分析显示男性、ESS得分、BMI为重度OSAHS的危险因素,男性相对危险度(OR值)为2.464[95%CI(1.136~5.347),P=0.023]; ESS得分OR值为1.089[95%CI(1.026~1.155),P=0.005]; BMI指数OR值为1.183[95%CI(1.094~1.279),P<0.001]。结论 重度OSAHS男性发生率高,日间嗜睡症状发生可能性更大,BMI更高,发生超重肥胖可能性更大,临床中应注意识别。

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更新日期/Last Update: 2020-10-20