[1]陈 硕 施小龙.腹腔镜下卵巢肿瘤剥除术对卵巢储备功能的影响[J].福建医药杂志,2020,42(05):16-18.
　CHEN Shuo,SHI Xiaolong.Effect of laparoscopic ovarian cystectomy on ovarian reserve[J].FUJIAN MEDICAL JOURNAL,2020,42(05):16-18.
点击复制

腹腔镜下卵巢肿瘤剥除术对卵巢储备功能的影响()
分享到：

《福建医药杂志》[ISSN:1002-2600/CN:35-1071/R]

卷:
42
期数:
2020年05期
页码:
16-18
栏目:
临床研究
出版日期:
2020-10-20

文章信息/Info

Title:
Effect of laparoscopic ovarian cystectomy on ovarian reserve
文章编号:
1002-2600(2020)05-0016-04
作者:
陈 硕 施小龙1
福建医科大学省立临床医学院 福建省立金山医院妇产科(福州 350001)
Author(s):
CHEN Shuo; SHI Xiaolong
Department of Obstetrics and Gynecology, South Branch of Fujian Provincial Hospital, Provincial Clinical Medical College of Fujian Medical University, Fuzhou, Fujian 350001,China
关键词:
抗苗勒氏管激素;  卵巢肿瘤剥除术;  卵巢子宫内膜异位囊肿
Keywords:
anti-Mü; llerian hormone;  ovarian cystectomy;  ovarian endometrioma
分类号:
R737.31
文献标志码:
B
摘要:
目的 研究腹腔镜下卵巢肿瘤剥除术对卵巢储备功能的影响。方法 选取我院2017年1月至2019年12月收治的卵巢良性肿瘤患者51例进行回顾性分析。将其分为两组,25例为卵巢子宫内膜异位囊肿(ovarian endometrioma,OMA),26例为非卵巢子宫内膜异位囊肿(non-endometrioma, non-OMA),比较术前及术后1个月血清抗苗勒氏管激素(anti-Müllerian hormone,AMH)水平,评估腹腔镜下卵巢肿瘤剥除术对卵巢储备功能的影响。结果 年龄与术前血清AMH水平呈显著负相关性(P<0.001); 体质指数(body mass index, BMI)与AMH无相关性; 两组术后AMH水平均较术前显著下降(P<0.05)。结论 腹腔镜下卵巢肿瘤剥除术对卵巢储备能力产生负面影响。
Abstract:
Objective To determine whether ovarian reserve is compromised after laparoscopic ovarian cystectomy.Methods A retrospective study was conducted among 51 women who underwent laparoscopic ovarian cystectomy at Department of Obstetrics and Gynecology, South Branch of Fujian Provincial Hospital, China, between January 1st, 2017 and December 15th, 2019.The patients were divided into ovarian endometrioma(OMA)group(n=25)and non-endometrioma(non-OMA)group(n=26).Serum level of anti-Müllerian hormone(AMH)was measured to assess ovarian function before undergoing the procedure(baseline)and at one month after surgery(postoperative period).Results Age was negatively correlated with the serum AMH level at baseline(P<0.001).No correlation was found between AMH and body mass index(BMI).Serum AMH levels were lower in the postoperative period versus the preoperative period in both two groups(P<0.05).Conclusion Laparoscopic ovarian cystectomy compromised ovarian reserve.

参考文献/References:

[1] Iwase A,Hirokawa W,Goto M,et al.Serum anti-Müllerian hormone level is a useful marker for evaluating the impact of laparoscopic cystectomy on ovarian reserve[J].Fertility and Sterility, 2010, 94(7): 2846-2849.
[2] Somigliana E, Ragni G,Infantino M,et al.Does laparoscopic removal of nonendometriotic benign ovarian cysts affect ovarian reserve?[J].Acta Obstetricia Et Gynecologica Scandinavica, 2006, 85(1): 74-77.
[3] Yuan Z,Cao D,Bi X,et al.The effects of hysterectomy with bilateral salpingectomy on ovarian reserve[J].International Journal of Gynecology & Obstetrics, 2019, 145(2): 233-238.
[4] Nilsson-Condori E,Hedenbro J L,Thurin-Kjellberg A,et al.Impact of diet and bariatric surgery on anti-Müllerian hormone levels[J].Human Reproduction, 2018, 33(4): 690-693.
[5] Hart R J,Hickey M,Maouris P,et al.Excisional surgery versus ablative surgery for ovarian endometriomata[J].Cochrane Database of Systematic Reviews, 2008(2): 1-24.
[6] Somigliana E,Arnoldi M,Benaglia L,et al.IVF-ICSI outcome in women operated on for bilateral endometriomas[J].Human Reproduction, 2008, 23(7): 1526-1530.
[7] Muzii L,Bianchi A,Crocè C,et al.Laparoscopic excision of ovarian cysts: is the stripping technique a tissue-sparing procedure?[J].Fertility and Sterility, 2002, 77(3): 609-614.
[8] Muzii L,Bellati F,Bianchi A,et al.Laparoscopic stripping of endometriomas: a randomized trial on different surgical techniques.Part II: pathological results[J].Human Repro-duction, 2005, 20(7): 1987-1992.
[9] Maneschi F,Marasá L,Incandelaet S,et al.Ovarian cortex surrounding benign neoplasms: a histologic study[J].American Journal of Obstetrics Gynecology, 1993, 169(2): 388-393.
[10] Muzii L,Bellati F,Palaia I,et al.Laparoscopic stripping of endometriomas: a randomized trial on different surgical techniques.Part I: Clinical results[J].Human Reproduction, 2005, 20(7): 1981-1986.
[11] Baracat C M F,Abdalla-Ribeiro H A S,Araujo R S D C,et al.The impact on ovarian reserve of different hemostasis methods in laparoscopic cystectomy: a systematic review and meta-analysis[J].Revista Brasileira de Ginecologia e Obstetrícia/RBGO Gynecology and Obstetrics, 2019, 41(6): 400-408.

备注/Memo

备注/Memo:
基金项目:福建医科大学启航基金(2018QH1118) 1 通信作者,Email:xiaolong6070@126.com
更新日期/Last Update: 2020-10-20